Base case | Sensitivity analysis | Source | ||
---|---|---|---|---|
IORT | IMRT | IORT | ||
Transition probabilities | ||||
LR after BCS year 1 | 0.000 | 0.002 | 0.000 | |
LR after BCS year 2 | 0.001 | 0.004 | 0.000 | |
LR after BCS year 3 | 0.018 | 0.004 | 0.010 | |
LR after BCS year 4 | 0.009 | 0.011 | 0.008 | |
LR after BCS year 5 | 0.005 | 0.000 | 0.006 | |
LR after BCS year 6 | 0.016 | 0.000 | 0.011 | |
LR after BCS year 7 | 0.001 | 0.004 | 0.002 | |
LR after BCS year 8 | 0.012 | 0.008 | 0.010 | |
LR after BCS year 9 | 0.010 | 0.000 | 0.008 | |
LR after BCS year 10 | 0.006 | 0.000 | 0.005 | |
Metastasis after LR | 0.03 | 0.03 | – | [16] |
Metastasis after RF | 0.006 | 0.0029 | 0.004 | |
Death by any cause 50–54 | 0.002 | [15] | ||
Death by any cause 55–59 | 0.004 | [15] | ||
Death by any cause 60–64 | 0.006 | [15] | ||
Death by any cause 65–69 | 0.009 | [15] | ||
Death by breast cancer year 1 | 0.003 | 0.004 | ||
Death by breast cancer year 2 | 0.002 | 0.004 | ||
Death by breast cancer year 3 | 0.006 | 0.006 | ||
Death by breast cancer year 4 | 0.008 | 0.006 | ||
Death by breast cancer year 5 | 0.017 | 0.006 | ||
Death by breast cancer year 6 | 0.018 | 0.003 | ||
Death by breast cancer year 7 | 0.006 | 0.012 | ||
Death by breast cancer year 8 | 0.011 | 0.010 | ||
Death by breast cancer year 9 | 0.008 | 0.017 | ||
Death by breast cancer year 10 | 0.018 | 0.005 | ||
Costs | ||||
Treatment cost | $418 | $29 | – | |
Other direct cost | $359 | $294 | – | |
Annual maintenance cost | $55,344 | – | – | |
Health state utilities | ||||
Disease free | 0.920 | [17] | ||
Local recurrence | 0.779 | [17] | ||
Other recurrences | 0.685 | [17] |