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Table 4 Mean annual treatment cost of each epilepsy patient with respect to top five prescribing anti-epileptic drugs as monotherapy

From: Analysis of treatment adherence and cost among patients with epilepsy: a four‐year retrospective cohort study in Pakistan

 

Mean cost for Continuers

Mean cost for Switchers

Mean cost for Discontinuers

Mean cost for study cohort

 

PKRa± SDb

USDc± SD

PKR ± SD

USD ± SD

PKR ± SD

USD ± SD

PKR ± SD

USD ± SD

Levetiracetam

14709.5 ± 3297.2

90.4 ± 20.2

6058.7 ± 1435.3

37.2 ± 8.8

6246.5 ± 1278.2

38.3 ± 7.8

9004.9 ± 2003.5

55.3 ± 12.3

Valproic acid

3723.1 ± 912.2

22.8 ± 5.6

8425.3 ± 2038.4

51.7 ± 12.5

1487.6 ± 437.6

9.14 ± 2.6

4545.5 ± 1129.4

27.9 ± 6.9

Carbamazepine

1350.5 ± 405.7

8.3 ± 2.4

7468.6 ± 1974.2

45.9 ± 12.1

853.7 ± 237.9

5.2 ± 1.4

3224.2 ± 872.6

19.8 ± 5.3

Lamotrigine

22995.2 ± 4397.3

141.3 ± 27.0

9574.5 ± 2044.9

58.8 ± 12.5

9657.2 ± 1949.2

59.3 ± 11.9

14075.5 ± 2797.1

86.5 ± 17.1

Lacosamide

18980.1 ± 3743.6

116.6 ± 23.0

11478.0 ± 2187.3

70.5 ± 13.4

8574.1 ± 1887.3

52.6 ± 11.5

13010.6 ± 2606.0

79.9 ± 16.0

Others

7665.0 ± 1825.5

47.1 ± 11.2

11485.8 ± 2295.6

70.6 ± 14.1

2547.6 ± 578.7

15.6 ± 3.5

7232.8 ± 1566.6

44.4 ± 9.6

Total Mean Cost

11570.5 ± 2430.2

71.1 ± 14.9

9081.8 ± 1995.9

55.8 ± 12.2

4894.4 ± 1061.4

30.0 ± 6.5

8515.5 ± 1829.2

52.3 ± 11.2

Total annual cost

69423.0 ± 14581.5

426.6 ± 89.6

54490.9 ± 11975.7

334.9 ± 73.6

29366.6 ± 6368.9

180.4 ± 39.1

51093.5 ± 10975.3

314.0 ± 67.4

  1. Phenobarbital, phenytoin, gabapentin, pregabalin and oxcarbazepine were categorized as others AEDs
  2. aPakistani rupees
  3. bStandard deviation
  4. cUnited States Dollar
  5. *1 USD = 154.38 PKR (At: 27-Jan-2020)