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Table 4 Sensitivity analysis 2 - Influence of PDC rates on health care expenditures

From: Effects of adherence to pharmacological secondary prevention after acute myocardial infarction on health care costs – an analysis of real-world data

N = 7532

 

Estimate

Std. Error

t value

Pr(>|t|)

(Intercept)

 

10,032.21

840.93

11.93

0.0000***

Age

55 < 65

−105.27

573.67

−0.18

0.8544

 

65 < 75

−44.58

537.60

−0.08

0.9339

 

≥ 75

− 1067.64

546.18

−1.95

0.0507

Gender

female

−58.70

274.20

−0.21

0.8305

BMI

underweight

1949.13

1756.07

1.11

0.2671

 

overweight

− 228.12

331.73

−0.69

0.4917

 

obese

− 140.00

352.75

−0.40

0.6915

BIMD 2010 (Q1 least deprived, Q5 most deprived)

Q2

−505.20

371.50

−1.36

0.1739

 

Q3

− 738.01

404.06

−1.83

0.0678

 

Q4

− 545.68

398.88

−1.37

0.1713

 

Q5

−768.79

376.58

−2.04

0.0412*

Smoker

yes

183.30

387.00

0.47

0.6358

NYHA

1

1852.93

707.26

2.62

0.0088**

 

2

1539.45

414.21

3.72

0.0002***

 

3

2743.89

381.06

7.20

0.0000***

 

4

4034.88

422.76

9.54

0.0000***

DMP COPD

yes

310.39

477.84

0.65

0.5160

DMP asthma

yes

− 681.41

731.89

−0.93

0.3519

DMP diabetes type 1

yes

2067.03

1966.07

1.05

0.2931

DMP diabetes type 2

yes

424.88

253.61

1.68

0.0939

HMG assignments per month

 

1.41

0.24

5.77

0.0000***

Year after AMI

 

− 5133.93

155.94

−32.92

0.0000***

Angina pectoris

 

1766.07

249.36

7.08

0.0000***

Peripheral vascular disease

 

3727.85

358.26

10.41

0.0000***

Dyslipidemia

 

737.41

334.28

2.21

0.0274*

Congestive heart failure

 

1761.57

308.12

5.72

0.0000***

Hypertension

 

1925.66

520.03

3.70

0.0002***

Dialysis

 

25,186.07

1035.41

24.32

0.0000****

  

edf

Ref.df

F

p-value

s (PDC mean ACE inhibitors) male

 

1.00

1.00

0.26

0.6135

s (PDC mean ACE inhibitors) female

 

1.00

1.00

2.44

0.1179

s (PDC mean β-blockers) male

 

1.00

1.00

0.01

0.9286

s (PDC mean β-blockers) female

 

1.00

1.00

0.01

0.9118

s (PDC mean statins) male

 

1.00

1.00

3.84

0.0500

s (PDC mean statins) female

 

1.00

1.00

0.03

0.8529

s (PDC mean anti-platelet agents) male

 

2.43

2.43

10.20

0.0000***

s (PDC mean anti-platelet agents) female

 

1.00

1.00

9.76

0.0018**

s (PDC standard deviation ACE inhibitors) male

 

2.93

2.93

4.86

0.0023**

s (PDC standard deviation ACE inhibitors) female

 

2.87

2.87

6.88

0.0002***

s (PDC standard deviation β-blockers) male

 

4.70

4.70

17.23

0.0000***

s (PDC standard deviation β-blockers) female

 

1.00

1.00

3.78

0.0520

s (PDC standard deviation statins) male

 

1.18

1.18

1.06

0.3681

s (PDC standard deviation statins) female

 

3.59

3.59

3.45

0.0136*

s (PDC standard deviation anti-platelet agents) male

 

3.42

3.42

8.22

0.0000***

s (PDC standard deviation anti-platelet agents) female

 

2.93

2.93

9.49

0.0000***

  1. R-sq. (adj.) = 0.338
  2. Abbreviations: AMI (Acute Myocardial infarction), BIMD 2010 (Bavarian Index of Multiple Deprivation, year 2010), BMI (Body Mass Index), DMP (Disease Management Program), HMG (Hierarchical Morbidity Group), NYHA (New York Hear Association), PDC (Proportion of days covered)
  3. Significane Levels:* p < 0.05 ** p <0.01 *** p < 0.001