Skip to main content

Table 5 Applying the APEASE criteria to select useful intervention functions

From: Theory-driven development of a medication adherence intervention delivered by eHealth and transplant team in allogeneic stem cell transplantation: the SMILe implementation science project

Factors/barriers that need to change to perform target behavior (step 4)

Intervention function

Affordability

Practicability

(Cost-) Effectiveness

Acceptability

Side-effects/ Safety

Equity

Does the intervention function meet the APEASE criteria, comments why yes/no?

PhC: Lack of knowledge; lack of awareness / recognition in daily life

ReM: False beliefs about consequences and own responsibility for intended outcomes

Education

++

++

+

++

+

+

YES – provision of knowledge

SoO: Lack of awareness that medication intake can be improved by everyone involved in care

AuM: Poor relationship with health care provider; fear of embarrassment

ReM: False beliefs about own capabilities; behaviors incompatible with identity

Persuasion

+

+

+

++

++

++

YES – foster positive feelings, motivation; beliefs about capability, goals (self-efficacy)

 

Incentivization

–

±

–

±

+

±

NO – not effective and not affordable

 

Coercion

      

NO – Not acceptable

PsC: Lack of knowledge of drug intake procedure; lack of skills to develop coping strategies; limitations in memory & decision processes

PhO: Lack of facilitation via support for memory, concentration, attention

SoO: Lack of social or peer support

AuM: Lack of coping strategies

ReM: Lack of adaptive coping strategies

Training

+

+

+

+

++

++

YES – provision of training to prepare medication / use pill boxes / use reminders / self-monitoring

 

Restriction

      

Not applicable

 

Environmental restructuring

±

±

±

±

+

+

NO – not affordable (provision of administration aids)

SoO: Lack of positive role models

Modelling

+

+

+

++

++

++

YES – provision of peer learning, video

PhC: Limited physical stamina

PsC: Lack of habit-forming, goal-setting or action-planning; lack of behavioral regulation

PhO: Lack of facilitation via accessibility, easiness, availability, convenience

SoO: Lack of social or peer support

AuM: Lack of problem-solving strategies

ReM: Insufficient intention and goals

Enablement

+

+

+

+

++

++

YES – skills and strategies to deal with barriers (e.g., side effects, interruptions in daily routine)

  1. PhC Physical Capability, PsC Psychological Capability, PhO Physical Opportunity, SoO Social Opportunity, AuM Automatic Motivation, ReM Reflective Motivation
  2. (++ very promising) (+ promising) (± not promising but worth considering) (− unacceptable)