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Table 4 Medicines appearing on the WHO Model EMLs but not on the SA STG/EMLs

From: Quantitative evaluation of essential medicines lists: the South African case study

Section

Name of medicine (core list)

Name of medicine (complementary list)

2. Medicine for pain and palliative care

Docusate sodium

 

4. Antidotes and other substances used in poisoning

Potassium ferric hexacyano-ferrate(II)-2H2O

Sodium nitrite

Sodium thiosulfate

Fomepizole

Sodium calcium edetate

Succimer,

5. Anticonvulsants/antiepileptics

 

Ethosuximide

6. Anti-infective medicines

Levamisole (not registered in SA),

Niclosamide,

Pyrantel,

Diethylcarbamazine (not readily available in SA, can be obtained from pharma company),

Ivermectin (not registered in SA, can be obtained after MCC approval)

Triclabendazole (not available for human use in SA)

Azithromycin,

Trimethoprim (available in combination with Sulfamethoxazole),

Spectinomycin (not available in SA),

Clofazimine (available on named patient basis)

Ethambutol + Isoniazid

Ethambutol + Isoniazid + Rifampicin

Rifabutin

Flucytosine (available on named patient basis after MCC approval)

Griseofulvin

Potassium iodide

Atazanavir

Saquinavir

Indinavir

Lamivudine + nevirapine + stavudine (FDC)

Lamivudine + nevirapine + zidovudine (FDC)

Lamivudine + zidovudine (FDC)

Emtricitabine + Tenofovir (FDC)

Efavirenz + Emtricitabine + Tenofovir (FDC)

Oseltamivir

Ribavirin,

Diloxinide (not available in SA)

Miltefosine,

Paromomycin (not available in SA)

Sodium stibogluconate,

Amodiaquine (not available in SA)

Artemether (available in combination with lumefantrine)

Artesunate (not registered in SA, can be obtained through the IV artesunate access programme on a named patient basis after MCC approval)

Artesunate + amodiaquine (not available in SA)

Artesunate + mefloquine (not available in SA),

Mefloquine (not registered for treatment in SA)

Proguanil (not registered for treatment only prophylaxis and in combination with Atovaquone)

Sulfadoxine + Pyrimethamine (no longer recommended due to increased resistance)

Pyrimethamine

Sulfadiazine (available as silver sulfadiazine)

Pentamidine (not available in SA, available on named patient basis)

Suramin sodium (not readily available in SA, can be obtained on named patient basis)

Eflornithine (not readily available in SA, can be obtained on named patient basis)

Melarsoprol (not readily available in SA, can be obtained on named patient basis)

Nifurtimox (not available in SA)

Capreomycin,

Oxaminiquine (not available in SA)

Cycloserine (alternative terizidone is listed)

p-aminosalicylic acid (PAS),

potassium iodide

Pegylated interferon alpha (2a or 2b)

8. Antineoplastic and immunosuppresives

 

Cytotoxics: Ciclosporin, asparaginase, calcium folinate, carboplatin, chlorambucil, mercaptopurine, cytarabine, dactinomycin, daunorubicin, dacarbazine, doxorubicin, docetaxel, mercaptopurine, mesna, thioguanine, etoposide, fluorouracil, ifosfamide, paclitaxel, procarbazine, vinblastine,

10. Medicines affecting the blood

protamine sulfate

 

12. Cardiovascular medicines

 

Sodium nitroprusside

13. Dermatological medicines (topical)

Sodium thiosulfate

Terbinafine

Mupirocin

Potassium permanganate

Urea

Fluorouracil

 

14. Diagnostic agents

Amidotrizoate

Meglumine iotroxate

15. Disinfectants and antiseptics

Glutaral

 

16. Diuretics

Amiloride

 

18. Hormones, other endocrine medicines and contraceptives

Estradiol cypionate + medroxyprogesterone acetate

Diaphragms

Levonorgestrel releasing implant

Potassium iodide,

Propylthiouracil (not available in SA)

 

19. Immunologicals

Tuberculin (PPD)

Diphtheria antitoxin

Cholera vaccine

Hepatitis A vaccine

Japanese encephalitis vaccine

Meningococcal meningitis vaccine

Mumps vaccine

Rotavirus vaccine

Rubella vaccine

Typhoid vaccine

Yellow fever vaccine

 

21. Ophthalmological preparations

Azithromycin

Latanoprost

Bevacizumab

23. Peritoneal dialysis solution

Intraperitoneal dialysis solution

 

24. Medicines for mental and behavioural disorders

Clomipramine

Nicotine replacement therapy

 

27. Vitamins and minerals

Ascorbic acid (only available in a multivitamin preparation)

Riboflavin (only available in a multivitamin preparation)

Sodium fluoride

 
  1. Note: The tertiary/quaternary EML was not considered in this analysis