Skip to main content

Table 3 Independent effect of baseline characteristics on medication adherencea

From: Clinical and demographic correlates of medication and visit adherence in a large randomized controlled trial

 

Odds ratio (95 % CI) - Multiple logistic regression

Full model

Reduced model

Baseline characteristic

(N = 28,176)

P-value

(N = 28,176)

P-value

Adequate Visit Adherence

0.97 (0.91–1.03)

0.330

  

Male

1.01 (0.94–1.07)

0.885

  

Age (55–64 is the ref group)

    

 65–74

0.92 (0.85–0.98)

0.014

0.91 (0.85–0.97)

0.007

 ≥75

0.82 (0.75–0.89)

<0.001

0.81 (0.74–0.88)

<0.001

Race and Ethnicity (Black is reference group)

    

 Non-Black Hispanic

0.76 (0.69–0.82)

<0.001

0.75 (0.69–0.82)

<0.001

 Non-Black Non-Hispanic

1.45 (1.36–1.55)

<0.001

1.45 (1.36–1.55)

<0.001

Education (High school is the reference group)

    

 < High school

0.91 (0.85–0.97)

0.006

0.91 (0.85–0.97)

0.006

 Beyond high school

1.02 (0.95–1.09)

0.645

1.02 (0.95–1.09)

0.654

Has diabetes

0.96 (0.90–1.02)

0.207

  

Smoking (Current is reference group)

    

 Past

1.13 (1.05–1.22)

0.001

1.13 (1.05–1.21)

0.001

 Never

1.15 (1.06–1.24)

<0.001

1.14 (1.06–1.23)

<0.001

Self-assessed baseline health (Excellent is reference group)

    

 Very good

0.93 (0.82–1.06)

0.283

0.93 (0.82–1.06)

0.287

 Good

0.90 (0.80–1.02)

0.096

0.90 (0.80–1.02)

0.093

 Fair

0.79 (0.70–0.90)

<0.001

0.79 (0.70–0.90)

<0.001

 Poor

0.94 (0.77–1.14)

0.515

0.94 (0.77–1.14)

0.509

 Unknown

0.89 (0.59–1.35)

0.590

0.89 (0.59–1.34)

0.568

Practice type (Private is reference group)

    

 Group

1.56 (1.44–1.70)

<0.001

1.56 (1.44–1.70)

<0.001

 HMO

2.00 (1.68–2.39)

<0.001

2.01 (1.68–2.40)

<0.001

 Community Health Center

1.22 (1.10–1.36)

<0.001

1.22 (1.10–1.36)

<0.001

 University

1.22 (1.10–1.35)

<0.001

1.21 (1.10–1.34)

<0.001

 Other

1.70 (1.52–1.90)

<0.001

1.70 (1.52–1.90)

<0.001

 VAMC

1.18 (1.08–1.29)

<0.001

1.18 (1.08–1.28)

<0.001

 Unknown

1.46 (1.28–1.68)

<0.001

1.48 (1.29–1.70)

<0.001

Baseline Medications (Untreated is reference group)

    

 On drug therapy < 2 months

1.24 (1.13–1.35)

<0.001

1.23 (1.13–1.35)

<0.001

 On drug therapy ≥ 2 months

1.11 (0.94–1.30)

0.225

1.11 (0.94–1.30)

0.224

HDL Cholesterol < 35 mg/dl

1.03 (0.94–1.12)

0.585

  

Taking aspirin

1.14 (1.07–1.21)

<0.001

1.13 (1.07–1.20)

<0.001

Possible disability

0.91 (0.84–0.99)

0.033

0.91 (0.84–0.99)

0.022

ASCVD (No ASCVD is reference group)

    

 Yes

0.94 (0.87–1.01)

0.082

0.95 (0.89–1.01)

0.117

 Sub-clinical

0.76 (0.71–0.82)

<0.001

0.77 (0.72–0.83)

<0.001

BMI > 30

1.05 (0.99–1.11)

0.105

  

Decile of clinic enrollment volume

1.05 (1.04–1.06)

<0.001

1.05 (1.04–1.06)

<0.001

Randomized treatment group (Chlorthalidone is reference group)

    

 Amlodipine

0.99 (0.93–1.05)

0.722

0.99 (0.93–1.05)

0.722

 Lisinopril

0.92 (0.86–0.98)

0.010

0.92 (0.86–0.98)

0.012

  1. aMedication adherence is a dichotomous variable defined as poor adherence if participants reported taking less than 80 % of their step 1 medication at any visit and as good if they reported taking 80 % or more of this medication at all visits