Table 5 Unintentional Non-Adherence as a Mediator on the Direct Effect of Patient Beliefs on Intentional Non-Adherence (N = 24,017)
From: Unintentional non-adherence to chronic prescription medications: How unintentional is it really?
| Â | Model 1 Direct effect of patient beliefs on unintentional non-adherence | Model 2 Direct effect of unintentional non-adherence on intentional non-adherence | Model 3 Total effect of patient beliefs on intentional non-adherence | Model 4 Direct effect of patient beliefs on intentional non-adherence controlling for unintentional non-adherence |
|---|---|---|---|---|
|  | Pathway a in Figure 1 | Pathway b in Figure 1 | Pathway c in Figure 1 | Pathway c’ in Figure 1 |
| Â | DV = unintentional non-adherence | DV = intentional non-adherence | DV = intentional non-adherence | DV = intentional non-adherence |
| Â | B (95% CI) | |||
Predictor Variables | Â | |||
Perceived Need for Prescription | Â | Â | Â | Â |
Quartile 1 | 9.2* (7.8–10.7) |  | 4.1* (3.4–4.9) | 2.7* (1.9–3.4) |
Quartile 2 | 7.5* (6.3–8.2) |  | 1.9* (1.3–2.6) | 0.8* (0.2–1.4) |
Quartile 3 | 5.1* (3.9–6.2) |  | 0.6 (−0.1–1.2) | −0.2 (−0.8–0.4) |
Prescription Affordability | Â | Â | Â | Â |
Quartile 1 | 18.5* (17.2–19.8) |  | 11.9* (11.2–12.6) | 9.0* (8.4–9.7) |
Quartile 2 | 10.0* (8.7–11.3) |  | 5.3* (4.6–5.9) | 3.7* (3.1–4.4) |
Quartile 3 | 5.1* (3.9–6.2) |  | 1.5* (0.9–2.1) | 0.7* (0.1–1.3) |
Prescription Concerns | Â | Â | Â | Â |
Quartile 1 | 4.5* (3.0–6.0) |  | 7.7* (6.9–8.5) | 7.0* (6.3–7.8) |
Quartile 2 | 3.3* (2.1–4.6) |  | 2.5* (1.8–3.1) | 2.0* (1.3–2.6) |
Quartile 3 | 2.8* (1.6–4.0) |  | 1.1* (0.4–1.7) | 0.6* (0.1–1.2) |
Unintentional Non-Adherence |  | 0.2* (0.2–0.2) |  | 0.2* (0.1–0.2) |