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Table 1 Elements of the PICOS question defined for this review

From: A systematic review and meta-analysis of community and primary-care-based hepatitis C testing and treatment services that employ direct acting antiviral drug treatments

 

Inclusion

Exclusion

Population

Age 18 years and over

Infected with hepatitis C

Age less than 18 years

Co-infection with Hepatitis B virus

Co-infection with HIV

Intervention

Provision of hepatitis C treatment in any primary care and community environments

Treatment using any direct acting antiviral therapy

Care provider could be any health care provider

Hepatitis C treatment in prison populations

Treatment with ribavirin / interferon regimes as the primary intervention

Comparison

Care in any hospital or secondary care environment or no comparison group

 

Outcome

Treatment uptake, treatment completion and SVR outcomes

 

Study design

Observational studies, retrospective or prospective cohort studies, randomised trials; conference abstracts; qualitative and mixed methods studies

Case studies; systematic reviews