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Table 3 Combinations of comorbidities and prolonged length of stay

From: Multimorbidity and healthcare resource utilization in Switzerland: a multicentre cohort study

Combinations of comorbidities a

OR (95% CI) b

Interaction c

Difference in median LOS (95% CI) d

Miscellaneous mental health disorders

Mood disorders

11.28 (8.71;14.61)

+

17.3 (16.5;18.3)

Diseases of white blood cells

Hematological malignancy

10.95 (9.06;13.24)

+

15.7 (15.1;16.8)

Chronic heart disease

Chronic ulcer of skin

4.83 (3.77;6.17)

+

7.8 (6.8;8.7)

Anxiety disorders

Mood disorders

4.10 (3.06;5.49)

0

7.6 (6.4;8.8)

Chronic heart disease

Diseases of white blood cells

3.92 (3.01;5.11)

0

8.0 (7.0;9.1)

Paralysis

Solid malignancy

3.37 (2.54;4.47)

0

6.6 (5.5;7.8)

Chronic heart disease

Liver disease

3.36 (2.76;4.08)

+

6.2 (5.5;7.0)

Chronic kidney disease

Chronic ulcer of skin

3.22 (2.40;4.31)

5.4 (4.2;6.5)

Chronic heart disease

Hematological malignancy

3.21 (2.62;3.92)

0

5.2 (4.3;6.0)

Chronic kidney disease

Hematological malignancy

3.16 (2.42;4.14)

0

4.3 (3.2;5.4)

Arthropathy and arthritis

Mood disorders

3.10 (2.42;9.96)

5.7 (4.8;6.7)

Paralysis

Other nervous system disorders

3.02 (2.40;3.78)

0

5.1 (4.2;6.0)

Miscellaneous mental health disorders

Chronic heart disease

3.01 (2.30;3.93)

0

4.8 (3.8;5.9)

Dementia

Mood disorders

2.95 (2.27;3;82)

5.6 (4.6;6.6)

Paralysis

Epilepsy; convulsions

2.92 (2.28;3.75)

0

5.0 (4.0;6.0)

Other nervous system disorders

Mood disorders

2.89 (2.28;3.66)

0

5.9 (5.0;6.9)

Chronic kidney disease

Liver disease

2.89 (2.19;3.80)

0

4.9 (3.8;6.1)

Dementia

Substance-related disorders

2.83 (2.13;3.75)

0

5.1 (3.9;6.2)

Other nervous system disorders

Cerebrovascular disease

2.79 (2.21;3.54)

0

4.6 (3.7;5.6)

Epilepsy; convulsions

Cerebrovascular disease

2.79 (2.09;3.73)

+

5.3 (4.2;6.5)

  1. Abbreviations: CI confidence interval, LOS length of stay, OR odds ratio
  2. a20 combinations with the highest OR for PAR
  3. bA prolonged length of stay was defined as a stay longer than or equal to the upper quartile (75%)
  4. cThe signs "+" and "-"represent a significant more than multiplicative effect and less than multiplicative effect, respectively, of the comorbidities found in the combination on the odds for a prolonged LOS. A more than multiplicative effect means that the OR of the combination is higher than the ORs of the single comorbidities multiplied together. The sign "0"means that there is no significant interaction
  5. dp-value < 0.001 for all. A confidence interval not overlapping the zero line means that the difference in median is significant