Table 5 Non-overdose and overdose death in different time-intervals following treatment start (n = 6871) and treatment cessation (n = 1650): crude mortality rates (CMR) per 1000 person-years and 95% confidence interval
1–2 weeks | 2–4 weeks | 2–6 months | 6 months and after | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | PY | CMR (CI) | n | PY | CMR (CI) | n | PY | CMR (CI) | n | PY | CMR (CI) | |
After treatment start | ||||||||||||
Non-overdose | 7 | 340 | 20.6 (5.3–35.8) | 2 | 335 | 6.0 (0.0–14.2) | 21 | 3124 | 6.7 (3.8–9.6) | 348 | 28,894 | 12.0 (10.8–13.3) |
Overdose | 2 | 340 | 5.9 (0.0–14.0) | 0 | 335 | 0 | 11 | 3124 | 3.5 (1.4–5.6) | 147 | 28,894 | 5.1 (4.3–5.9) |
After treatment stop | ||||||||||||
Non-overdose | 4 | 127 | 31.4 (0.6–62.2) | 3 | 112 | 26.7 (0.0–56.9) | 39 | 1008 | 38.7 (26.5–50.8) | 184 | 6700 | 27.5 (23.5–31.4) |
Overdose | 0 | 127 | 0 | 2 | 112 | 17.8 (0.0–42.5) | 28 | 1008 | 27.8 (17.5–38.1) | 129 | 6700 | 19.3 (15.9–22.6) |