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Table 2 All cause and cause-specific mortality rates, before, during and after treatment; crude mortality rates (CMR) per 1000 person-years and 95% confidence interval

From: From restrictive to more liberal: variations in mortality among patients in opioid maintenance treatment over a 12-year period

 

Pre-treatment (n = 7843)

In treatment (n = 6871)

After treatment (n = 1650)

n

PY

CMR (CI)

n

PY

CMR (CI)

n

PY

CMR (CI)

Overdose

68

4526

15.0 (11.5–18.6)

160

29,172

5.5 (4.6–6.3)

159

6819

23.3 (19.7–26.9)

Non-overdose

21

4526

4.6 (2.7–6.6)

218

29,172

7.5 (6.5–8.5)

71

6819

10.4 (8.0–12.8)

Accidents

5

4526

1.1 (0.1–2.1)

15

29,172

0.5 (0.3–0.8)

8

6819

1.2 (0.4–2.0)

Suicide

3

4526

0.7 (0.0–1.4)

15

29,172

0.5 (0.3–0.8)

7

6819

1.0 (0.3–1.8)

Cancer/cardiovascular

3

4526

0.7 (0.0–1.4)

60

29,172

2.1 (1.5–2.6)

16

6819

2.3 (1.2–3.5)

Other

10

4526

2.2 (0.8–3.6)

128

29,172

4.4 (3.6–5.1)

40

6819

5.9 (4.0–7.7)

All-causes

89

4526

19.7 (15.6–23.8)

378

29,172

13.0 (11.7–14.3)

230

6819

33.7 (29.4–38.1)