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Table 1 Characteristics of 200 patients who died during opioid agonist treatment, stratified by the cause of death

From: Mortality and causes of death among patients with opioid use disorder receiving opioid agonist treatment: a national register study

Variables

N

Total, N (%)

Drug-induced deaths

All other causes of death

N = 84, n (%)

N = 116, n (%)

Demographics

 Male gender

200

147 (74)

59 (70)

88 (76)

 Age, mean (SD)

200

48.9 (8.4)

46.9 (8.5)

50.3 (8.2)

 Region East,

200

89 (45)

30 (36)

59 (51)

 incl. Capital Oslo

 Region South

200

39 (20)

16 (19)

23 (41)

 Region West

200

44 (22)

26 (31)

18 (16)

 Region Mid-Norway

200

14 (7)

7 (8)

7 (6)

 Region North

200

14 (7)

5 (6)

9 (8)

 Disability/retirement pensiona

154

117 (76)

45 (70)

72 (80)

 Own homeb

162

125 (77)

54 (78)

71 (76)

OAT medication

 Methadone

199

109 (55)

46 (55)

63 (54)

 Buprenorphine

199

82 (41)

35 (42)

47 (41)

 Other

199

8 (4)

2 (2)

6 (5)

 OAT prescribed by GPs

156

106 (68)

42 (60)

64 (74)

Dose methadone (met) or buprenorphine (bup)

 < 60 mg met or < 8 mg bup

187

21 (11)

10 (12)

11 (10)

 60–120 mg met or 8–24 mg bup

187

141 (75)

62 (77)

79 (75)

 > 120 mg met or > 24 mg bup

187

25 (13)

9 (11)

16 (15)

Total duration of OAT

 < 4 years

188

36 (19)

14 (18)

22 (20)

 4–8 years

188

56 (30)

30 (38)

26 (24)

 8–12 years

188

49 (26)

18 (23)

31 (29)

 12–17 years

188

47 (25)

18 (23)

29 (27)

Comorbidities

 Charlson index score,

200

2.0 (0–12)

1.0 (0–9)

3.0 (0–12)

 median (min–max)

 Psychiatric admissionsc

200

56 (28)

26 (31)

30 (26)

 BZD/Z-hypnoticsd

177

76 (43)

28 (38)

48 (46)

 Psychotropic medicatione

156

44 (28)

12 (20)

32 (33)

 Previous non-fatal overdosef

200

59 (30)

30 (36)

29 (25)

  1. aOnly four patients had a retirement pension at the time of death (> 67 years). Among those who did not have a disability or retirement pension, two had paid work and the rest had work assessment allowance or social welfare
  2. bOwn home, rented or owned. Among those who did not have an own home, two were homeless; the rest lived in shelters, institutions, with friends/family or were in prison
  3. cPsychiatric admissions registered in the NPR in the last 5 years before death
  4. dBZD/Z-hypnotics prescribed at least once in the year before death
  5. eAntidepressants/antipsychotic medication prescribed at least once in the year before death
  6. fNon-fatal overdoses registered in the NPR or in OAT status reports in the last 5 years before death