Risk factors operating through intermediate variables | ||||||
---|---|---|---|---|---|---|
Parameter | Exposure parameters | Outcomes | Unit of change | Distribution of uncertainty range | Change in value of outcome (SE) | Notes |
 Total fat | % of total energy [49] | Total serum cholesterol (mmol/l) [71] | Per 1% energy total fat | Normal | 0.020 (0.005) |  |
 Saturated fat | % of total energy [49] | Total serum cholesterol (mmol/l) [71] | Per 1% energy saturated fat | Normal | 0.052 (0.003) |  |
 Monounsaturated fatty acids | % of total energy [49] | Total serum cholesterol (mmol/l) [71] | Per 1% energy MUFA | Normal | 0.005 (0.003) |  |
 Polyunsaturated fatty acids | % of total energy [49] | Total serum cholesterol (mmol/l) [71] | Per 1% energy PUFA | Normal | −0.026 (0.004) |  |
 Dietary cholesterol | mg/day [49] | Total serum cholesterol (mmol/l) [71] | Per 1 g/day dietary cholesterol | Normal | 0.0007 (0.0001) |  |
 Salt consumption | g/day [49] | Systolic blood pressure (mmHg) [72] | Per 100 mmol/24 h urinary sodium | Normal | 5.80 (1.71) | Grams of salt consumed per day converted into urinary sodium excretion. |
 Total energy | kJ/day [49] | BMI (kg/m2) [73] |  |  |  | Details of equations describing the relationship between energy intake and body weight for men and women can be found in Christiansen and Garby [74]. |