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Table 1 Disease specific data inputs for PRIMEtime CE (all age and sex specific), reproduction of table 1 in supplementary file of Cobiac et al. (with permission) [31]

From: PRIMEtime CE: a multistate life table model for estimating the cost-effectiveness of interventions affecting diet and physical activity

Disease

Data and methods

Coronary heart disease (CHD)

Incidence of CHD estimated from incidence rates of first acute myocardial infarction (derived from Hospital Episode Statistics [38]), adjusted using the proportion of unstable angina among all coronary events in the OXVASC study [39].

Mortality rates from the Office of National Statistics cause-specific death registrations (number of deaths where myocardial infarction was mentioned on the death certificate) [40].

Case fatality rates and baseline prevalence derived using DISMOD IIa [41].

Stroke

Incidence of first stroke estimated from the OXVASC study [39] and data from the General Practice Research Database [42].

Mortality rates from the Office of National Statistics cause-specific death registrations [40].

Case fatality rates and baseline prevalence derived using DISMOD II [41].

Type two diabetes

Incidence rates from the UK Clinical Practice Research Datalink [43].

Type two diabetes mortality rate ratios and prevalence estimated from the National Diabetes Audit 2011/12 [44].

Case fatality rates derived using DISMOD II [41].

Cirrhosis

Incidence rates from a population-based cohort study linking the Clinical Practice Research Datalink and Hospital Episode Statistics [45].

Mortality rates from the Office of National Statistics cause-specific death registrations [40].

Case fatality rates and baseline prevalence derived using DISMOD II [41].

Cancers

Incidence rates from Cancer Registrations Statistics, England, 2012 [46].

Mortality rates from the Office of National Statistics cause-specific death registrations [40].

Case fatality rates and baseline prevalence derived using DISMOD II [41].

  1. NB Background UK disease trends derived by Cobiac et al. using methodology from the global burden of disease project [31, 47, 48].
  2. aCase fatality refers to the annual mortality rate among prevalent cases