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Table 2 Optimal sample sizes and maximum ENBS values for WTP benchmarks

From: Using value of information methods to determine the optimal sample size for effectiveness trials of alcohol interventions for HIV-infected patients in East Africa

Scenarios

Outcomes

WTP value ($/QALY)

WTP benchmark

Source

Intervention duration (years)

Optimal sample size (each arm)

Maximum ENBS

$1014

1 x GDP/capita

[49]

20

NAa

< 0

$1124

HIV laboratory monitory strategy if two ART regimens are available

[46]

20

NAa

< 0

$1770

ICER of 20 year alcohol intervention

–

20

500

$11,309,000

$2473

HIV laboratory monitory strategy if three ART regimens are available (base case)

[46]

20

200

$ 67,400

$3042

3 x GDP/capita

[49]

20

NAa

< 0

$8000

ICER of 10 year alcohol intervention

–

10

500

$5,108,000

$31,000

ICER of 5 year alcohol intervention

–

5

240

$2,949,000

  1. aSince return on investment for a new trial was negative (ENBS < 0), conducting a new trial was not recommended for this scenario