Type of uncertainty | Description | Handled by: |
---|---|---|
Parameter uncertainty | Uncertainty in estimates of the values of the parameters used in the cost-effectiveness model, represented by the familiar concepts of standard deviation and standard error | Probabilistic sensitivity analysis |
Structural uncertainty | The assumptions made in constructing and populating cost-effectiveness models, such as the method used to extrapolate survival | Sensitivity analysis |
Methodological uncertainty | The analytical approaches used | Specification of a Reference Case of standard methods |
Generalisability | To what extent the model, assumptions and data represent the population for which the decision is being made | Sensitivity analysis |