From: Identifying diabetes cases from administrative data: a population-based validation study
Algorithm | Sensitivity (%) (95% CI) | Specificity (%) (95% CI) | PPV (%) (95% CI) | NPV (%) (95% CI) | Prevalence | Kappa | Probability+ | Probability- |
---|---|---|---|---|---|---|---|---|
Physician claims only | ||||||||
1 P | 76.4(75.8–77.1) | 99.2(99.2–99.3) | 92.3(91.9–92.7) | 97.2(97.1–97.3) | 9.01% | 0.82 | 92.1% | 3.21% |
2 P in 1 yr | 58.5(57.8–59.3) | 99.8(99.8–99.8) | 97.4(97.1–97.7) | 95.2(95.1–95.3) | 6.54% | 0.71 | 97.3% | 5.48% |
3 P in 1 yr | 41.2(40.5–42.0) | 99.9(99.9–99.9) | 98.3(98.0–98.6) | 93.3(93.2–93.4) | 4.57% | 0.55 | 98.1% | 7.58% |
Inclusion of prescription claims | ||||||||
1 Rx | 45.9(45.2–46.7) | 100.0(100.0–100.0) | 99.3(99.1–99.5) | 93.8(93.7–93.9) | 5.03% | 0.60 | – | 7.01% |
1 P or 1 Rx | 82.6(82.1–83.2) | 99.2(99.1–99.2) | 92.6(92.2–93.0) | 97.9(97.8–98.0) | 9.72% | 0.86 | 92.7% | 2.39% |
1 P and 1 Rx | 39.7(39.0–40.5) | 100.0(100.0–100.0) | 99.8(99.7–99.9) | 93.1(93.0–93.3) | 4.33% | 0.54 | – | 7.75% |
(2 P in 1 yr) or (1Rx and 1 P) | 65.9(65.1–66.6) | 99.8(99.8–99.8) | 97.6(97.4–97.9) | 96.0(95.9–96.1) | 7.35% | 0.77 | 97.6% | 4.55% |
Inclusion of hospital records | ||||||||
H | 9.8(9.4–10.3) | 99.9(99.9–100.0) | 95.6(94.6–96.6) | 90.1(89.9–90.2) | 1.12% | 0.16 | 92.3% | 11.18% |
H or 1 P | 77.9(77.2–78.5) | 99.2(99.1–99.2) | 92.0(91.6–92.5) | 97.3(97.3–97.4) | 9.21% | 0.83 | 92.3% | 3.01% |
H or 1 Rx | 48.6(47.9–49.4) | 99.9(99.9–99.9) | 98.5(98.2–98.8) | 94.1(94.0–94.2) | 5.38% | 0.62 | 98.3% | 6.69% |
H or (2 P in 1 yr) | 61.6(60.9–62.4) | 99.8(99.7–99.8) | 96.9(96.6–97.3) | 95.5(95.4–95.6) | 6.92% | 0.73 | 97.4% | 5.09% |
H or (3 P in 1 yr) | 45.7(44.9–46.4) | 99.9(99.8–99.9) | 97.6(97.2–97.9) | 93.8(93.6–93.9) | 5.10% | 0.59 | 98.2% | 7.04% |
Physician claims, hospital records, prescription claims | ||||||||
(H or (2 P in 1 yr)) or 1 Rx | 73.1(72.5–73.8) | 99.7(99.7–99.8) | 97.1(96.8–97.4) | 96.8(96.7–96.9) | 8.21% | 0.82 | 96.8% | 3.62% |
(H or 1 P) and (1 Rx or 1 F) | 67.3(66.6–68.0) | 99.8(99.7–99.8) | 97.3(97.0–97.6) | 96.1(96.0–96.2) | 7.53% | 0.78 | 97.6% | 4.37% |
(H or 1 P) and 1 F | 56.4(55.7–57.2) | 99.8(99.8–99.8) | 96.9(96.5–97.2) | 94.9(94.8–95.0) | 6.34% | 0.69 | 97.2% | 5.74% |
(H or 1 P) and 1 Rx | 40.6(39.9–41.4) | 100.0(100.0–100.0) | 99.8(99.7–99.9) | 93.2(93.1–93.4) | 4.43% | 0.55 | – | 7.65% |