Table 2 Demographic and clinical characteristics
From: Impact on healthcare resource utilization of multiple sclerosis in Spain
EDSS 0–3.5 | EDSS 4.0–9.5 | Total | p-value | |
|---|---|---|---|---|
N = 152 | N = 70 | N = 222 | ||
Geographic regions in Spain, % | ||||
Asturias | 30.9 | 22.9 | 28.4 | 0,587 |
Catalonia | 69.1 | 77.1 | 71.6 | 0,827 |
Age, years, mean (SD) | 42.5 (11.5) | 52.2 (12.2) | 45.5 (12.5) | <0.001 |
Gender, female, N (%) | 68.4 | 65.7 | 64.4 | 0.292 |
Time since diagnostic, years, mean (SD) | 10.5 (7.6) | 19.8 (10.2) | 13.4 (9.5) | <0.001 |
MS type, % | ||||
RRMS | 74.3 | 35.7 | 62.2 | <0.001 |
SPMS | 13.8 | 50.0 | 25.2 | <0.001 |
PPMS | 7.2 | 14.3 | 9.5 | 0.009 |
CIS | 4.6 | 0.0 | 3.2 | <0.001 |
Relapses during follow-up | ||||
Number of relapses, mean (SD) | 0.4 (0.6) | 1.2 (1.0) | 0.7 (0.9) | <0.001 |
Proportion of population, N (%) | ||||
≥ 1 | 36.8 | 67.1 | 46.4 | <0.001 |
1 | 29.6 | 18.6 | 26.1 | 0.008 |
2 | 6.6 | 40.0 | 17.1 | <0.001 |
3 | 0.7 | 8.6 | 3.2 | 0.790 |
Comorbidity, mean (SD) | ||||
Number of comorbidities | 4.5 (2.7) | 6.0 (3.3) | 5.0 (3.0) | 0.001 |
Charlson Index | 0.7 (0.6) | 1.0 (0.7) | 0.8 (0.6) | 0.005 |
RUBs, mean | 2.9 (0.8) | 3.2 (0.7) | 3.0 (0.8) | 0.003 |
Proportion of population, N (%) | ||||
1 (healthy o very low morbidity) | 3.3 | 0.0 | 2.3 | <0.001 |
2 (low morbidity) | 25.7 | 14.3 | 22.1 | 0.038 |
3 (moderate morbidity) | 52.0 | 54.3 | 52.7 | 0.873 |
4 (high morbidity) | 18.4 | 28.6 | 21.6 | 0.041 |
5 (very high morbidity) | 0.7 | 2.9 | 1.4 | 0.031 |