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Table 4 Effect of changes in the base-case assumptions on the unit cost of MODS and Xpert, (US $)

From: Cost-effectiveness analysis of microscopic observation drug susceptibility test versus Xpert MTB/Rif test for diagnosis of pulmonary tuberculosis in HIV patients in Uganda

Type of test/parameter

Effect on cost

Increase/decrease (%)

MODS (base estimate US$ 6.53)

-Reduce useful life of capital equipment from 10 to 5 years

8.04

+23

-Reduce number of tests to 5 each day

11.8

+ 81

-Double price of consumables

7.8

+ 19

-Allocate 100 % of shared equipment & staff time to MODS

8.9

+ 36

Xpert (base estimate US$ 12.41)

-Increasing useful life of Xpert from 5 to 10 years

6.5

- 48

-Reduce number of tests to 5 each day

11.8

- 5

-Reduce price of cartridge by half

7.1

- 43

- Allocate 100 % of staff time to Xpert

13.2

+ 6