Table 3 Cost-effectiveness estimations for different interventions in patients with coronary artery disease
From: Advocacy for outpatient cardiac rehabilitation globally
Author (year) | Intervention | Patient population | Estimated savings |
|---|---|---|---|
Ades et al. (1997) [46] | CR versus with other post-MI treatment interventions | Post MI or revascularization | CR was found to result in savings of 2,130 $/YLS in 1980, which was projected to be 4,950 $/YLS for 1995 |
Johanneson et al. (1997) [47] | Statins (i.e., Simvastatin) versus no statins | Angina or MI | Simvastatin use resulted in $3,800 to $27,400 cost per year of life gained |
Cleland et al. (1997) [48] | CABG + Medical therapy + aspirin versus CABG + medical therapy + aspirin + statin versus medical+aspirin+statin versus medical + aspirin | Chronic stable angina | $36,709, $55,156 and $23,730 per QALY for each comparison over 5 years |
Chan et al. (2007) [49] | High intensity versus low intensity statin | Acute coronary syndrome, Chronic coronary disease | From $20,000 to $35,000 if cost difference of statins is between $2 and $3.50 From $70,000 to $125,000 if cost difference of statins is between $2 and $3.50 |
Dendale et al. (2008) [50] | CR versus no CR | Post PCI | Reduction in total health care costs with CR (€4,862/patient versus €5,498 Euro/patient) |
Weinbtraub et al. (2008) [51]a | PCI and medical therapy versus Medical therapy alone | Stable angina | $168,000 to $300,000 per QALY gained with PCI |
Wilson et al. (2012) [52] | Smoking cessation with varenicline plus counseling versus counseling only | CVD | Savings ranging from €5151 - €6120 per QALY gained |
Smith et al. (2013) [53] | Implantable cardiac defibrillator versus no defibrillator | Primary prevention of sudden death in patients with left ventricular ejection fraction <40% (ischemic and non-ischemic) | €43,993 per QALY gained compared to no defibrillator |