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Fig. 3 | BMC Health Services Research

Fig. 3

From: Transitioning from cytology-based screening to HPV-based screening at longer intervals: implications for resource use

Fig. 3

Estimated volumes of a HPV tests; b cytology tests; c high grade cytology results; d colposcopies; and e precancer treatments under the new proposed pathway with and without the impact of HPV vaccination: comparison of predictions from simple versus detailed method. High grade cytology results: those with a result of HSIL or ASC-H (Atypical squamous cells, possible high grade lesion) in The Bethesda System 2001; this is equivalent to possible HSIL in the Australian Modified Bethesda System 2004. High grade cytology results do not include those performed as a reflex test for women testing positive for HPV 16/18 at the primary test, nor those resulting from samples collected at colposcopy. Approximate vaccine impact = assumes rates as per cohorts offered vaccination at age 12 for all women born in 1981 or later (ie aged 26 or less throughout 2007), and rates as per unvaccinated cohorts for women born before 1981. No vaccine impact = estimates in the absence of HPV vaccination. Detailed method with vaccination = incorporates the effect of HPV vaccination (including indirect protection of unvaccinated individuals) based on observed uptake in individual birth cohorts

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