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Table 6 Selection of Studies for Re-assessment

From: The Systematic Guideline Review: Method, rationale, and test on chronic heart failure

Publication Type

No. of Cited

No. of Excluded

Reason for Preclusion

Systematic Reviews/Meta-analyses (SR)

36

13

Results outdated by more recent SR

  

3

SR reported surrogate outcomes where clinical outcomes were available

  

2

SR did not contain target population

  

4

SR was out of the scope of the target guideline

Randomized Controlled Trials (RCT)

170

132

RCT included in re-evaluated SR

  

8

Results on surrogate outcomes where clinical outcomes were available

  

12

Set aside for further comprehensive research

  

12

RCT was out of the scope of the target guideline

Traditional Reviews, Editorials

33

33

Provided no systematic evidence

Miscellaneous Clinical Studies

70

69

Study design and/or sample size N<50 were not expected to provide strong evidence; further search for high-level evidence was seen to be more effective than re-appraisal

Total

309

288

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