Table 1 Model outcomes for several compliance losses with generic substitution
Branded Risp. | Generic Risp. 0% | Generic Risp. 2.5% | Generic Risp. 5% | Generic Risp. 7.5% | Generic Risp. 10% | |
|---|---|---|---|---|---|---|
# Relapses | 3.98 | 3.98 | 3.99 | 4.01 | 4.02 | 4.04 |
Total relapse time (yrs) | 2.05 | 2.05 | 2.06 | 2.07 | 2.07 | 2.08 |
Average PANSS score | 62.9 | 62.9 | 63.0 | 63.2 | 63.4 | 63.5 |
Time on risperidone (yrs) | 1.16 | 1.16 | 1.14 | 1.13 | 1.12 | 1.10 |
% on risperidone after 1 yr | 60.7% | 60.7% | 59.3% | 57.9% | 56.5% | 55.1% |
Total QALYs (disc) | 3.622 | 3.622 | 3.618 | 3.615 | 3.611 | 3.607 |
Costs (discounted by component) | ||||||
Home (pp) | €0 | €0 | €0 | €0 | €0 | €0 |
Home (ia) | €254 | €254 | €255 | €256 | €257 | €258 |
Sheltered Living | €7,120 | €7,124 | €7,136 | €7,145 | €7,159 | €7,182 |
Day Care | €35,188 | €35,229 | €35,329 | €35,479 | €35,654 | €35,758 |
Hospital | €37,124 | €37,088 | €37,440 | €37,700 | €37,971 | €38,267 |
Long-term care institution | €958 | €953 | €966 | €965 | €972 | €973 |
Psych Visits | €952 | €952 | €954 | €955 | €957 | €959 |
Drug Costs | €8,012 | €6,778 | €6,772 | €6,765 | €6,760 | €6,755 |
Total Discounted Costs | €89,607 | €88,378 | €88,850 | €89,265 | €89,730 | €90,152 |
ΔE | 0 | 0.004 | 0.007 | 0.011 | 0.015 | |
ΔC | €1,230 | €757 | €343 | -€123 | -€544 | |
ICUR | - | €196,243 | €46,032 | dominant | dominant |