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Table 1 Nonadherence in antidepressant use: results of the binomial multilevel analyses on early dropouts and continuers and on refill nonadherence

From: Patient risk profiles and practice variation in nonadherence to antidepressants, antihypertensives and oral hypoglycemics

 

Early dropout (0 = continuer; 1 = early dropout)

Refill adherence (0 = adherent > 80%; 1 = nonadherent)

 

Oddsratioa)

95% CI

Oddsratioa)

95% CI

Socio-demographic characteristics

    

-age (mean; SD)

1.00

[0.99–1.01]

1.00

[1.00–1.00]

-% woman

0.78*

[0.63–0.95]

1.00

[0.84–1.19]

-% college/university

1.05

[0.80–1.36]

0.86

[0.69–1.09]

-% non-western

2.47*

[1.70–3.60]

2.59*

[1.75–3.82]

-% private insurance

1.06

[0.85–1.33]

0.95

[0.78–1.15]

-% living together

1.02

[0.80–1.29]

1.00

[0.82–1.21]

-% with job/study

1.26

[1.00–1.60]

0.88

[0.73–1.07]

Use of medication

    

Antidepressants

    

- % users of SSRIs

0.80

[0.59–1.08]

1.27*

[1.04–1.63]

- % users of TCAs

1.55*

[1.14–2.11]

0.76*

[0.58–0.99]

- % users of other antidepressants

reference

 

reference

 

Complex regime

    

number of other ATCs (mean;sd)

1.02

[1.00–1.05]

0.97*

[0.95–0.99]

Health & morbidity in general practice

    

Self-reported health

    

% excellent/good

1.20

[0.98–1.47]

1.17

[0.99–1.37]

Diagnoses for which GP is consulted (% of patients)

    

Depression (P03/P76)

0.62*

[0.50–0.76]

0.91

[0.77–1.07]

Anxiety (P01/P74)

0.75*

[0.57–0.98]

1.15

[0.93–1.42]

Neurasthenia (P78)

2.01*

[1.34–3.04]

0.82

[0.51–1.31]

Other diagnoses in P-chapter (P01–P99)

1.18

[0.95–1.47]

1.17

[0.97–1.41]

GP consultation for chronic diseases and overall contact

    

Number of other chronic complaints (mean, SD)

1.14*

[1.05–1.24]

1.18*

[1.09–1.27]

Number of contacts with GP (mean; SD)

0.99

[0.98–1.00]

0.99

[0.98–1.00]

Number of patients (N)

4,877

3,777

  1. * P < 0.05
  2. a) odds ratio > 1: more likely to be an early dropout; odds ratio < 1: less likely to be an early dropout