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Table 2 Estimates of sample sizes to detect a prescribing difference of 10% (with two-tailed test)

From: Randomised controlled trials for evaluating the prescribing impact of information meetings led by pharmacists and of new information formats, in General Practice in Italy

 

ATC code

Estimate of ICC

Sample size (NCP)

macrolides

J01FA

0.024

68

fluoroquinolones

J01MA

0.030

68

antidepressants

n06ab

0.058

88

nitroderivatives

C01da02, 05,08,14

0.09

96

bifosphosphonates (15% diff)

M05ba

0.062

106

proton pump inhibitors

A02BC

0.087

108

phosphomicine

J01xx01

0.014

108

Alfa blockers (for IPB)

g04ca + g04bx49

0.075

116

doxazosin (for IPB)

c02ca04

0.038

128

long acting β2 broncodilators + corticosteroids

R03AK06 e R03AK07

0.092

148

Finasteride +dutasteride

g04cb

0.08

154

opioids

N02A

0.061

164

clarithromicine

J01fa09

0.02

172

esomeprazole

A02bc05

0.023

204

long acting β2 broncodilators

R03AC12 e R03AC13

0.033

208

alendronate

M05ba04

0.08

218

finasteride

g04cb01

0.1

220

salmeterol + corticosteroids

R03ak06

0.102

234

bifosphosphonates

M05ba

0.062

238

azitromicine

J01fa10

0.068

266

risedronate

M05ba07

0

374

norfloxacine

J01ma06

0.055

386

fentanyl

N02ab03

0.043

428

salmeterol

R03ac12

0.053

698

morphine

N02aa01

0.05

2224

buprenorphine

N02ae01

0

Nc

bicalutamide

l02bb03

0

Nc

escitalopram

N06ab10

0

1434

levocetirizine

R06ae09

0.032

>600

antiandrogens

L02bb01+ L02bb03

0

nc