Effect of a restrictive transfusion strategy on transfusion-attributable severe acute complications and costs in the US ICUs: a model simulation

Table 4 Annual packed red blood cell transfusions avoided with restrictive transfusion strategy

Population variables	Input	Source	Output
Units pRBC TF/pt placebo arm	3.01	Corwin 2002 [16]	3.01
Units pRBC TF/pt restrictive group	1.74	Hebert [15]	1.74
Total units pRBC TF at risk ICU patients in 1 year
Current practice	1,020,800 x 3.01		3,073,360
Restrictive practice	1,020,800 x 1.74		1,778,234
Total units avoided in 1 year with restrictive strategy	3,073,360–1,778,234		1,295,126
pRBC units/1 TSAC	1,624/49	Table 3	33
Total TSACs avoided	1,295,126/33		39,246

PRBC, packed red blood cells; TF, transfusion; pt, patient; TSAC, transfusion-attributable severe acute complication

ISSN: 1472-6963