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Table 3 Transfusion-attributable severe acute complications and units packed red blood cells/1 transfusion-attributable severe acute complications derivation*

From: Effect of a restrictive transfusion strategy on transfusion-attributable severe acute complications and costs in the US ICUs: a model simulation

Population variable

Input

Source

Output

CV SAC

   

   Liberal

88 (21.0%)

Hebert 1999 [15]

 

   Restrictive

55 (13.2%)

Hebert 1999 [15]

 

   CV TSAC

88-55

Hebert 1999 [15]

33 (7.8%, 95% CI 2.7–12.9%)

ARDS SAC

   

   Liberal

48 (11.4%)

Hebert 1999 [15]

 

   Restrictive

32 (7.7%)

Hebert 1999 [15]

 

   ARDS TSAC

48-32

Hebert 1999 [15]

16 (3.8%, 95% CI–0.2–7.8%)

CV+ARDS TSAC

33+16

 

49

Total pRBC units TF liberal

5.6 u/pt x 420 pts TF

Hebert 1999 [15]

2,352

Total pRBC TF restrictive

2.6 u/pt x (418 x 0.67) pts TF

Hebert 1999 [15]

728

pRBC units TF excess

2,352–728

 

1,624

pRBC units/1 TSAC

1,624/49

 

33

  1. * CV SAC, cardiovascular severe acute complication; CV TSAC, cardiovascular transfusion-attributable severe acute complication; ARDS SAC, adult respiratory distress syndrome severe acute complication; ARDS TSAC, adult respiratory distress syndrome transfusion-attributable severe acute complication