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Table 5 Sensitivity analysis estimates of cost difference, and the additional number of live birth-producing pregnancies by the estimated cost difference of providing "IUI+IVF" compared to primary offer of IVF, varied sequentially.

From: Cost-effectiveness of primary offer of IVF vs. primary offer of IUI followed by IVF (for IUI failures) in couples with unexplained or mild male factor subfertility

Variable varied

Cost difference £ [("IUI+IVF") - IVF]

S-IUI

1 cycle of IUI

2 cycles of IUI

3 cycles of IUI

4 cycles of IUI

5 cycles of IUI

6 cycles of IUI

LBR = 8.7%

£43,100

£111,900

£183,400

£257,400

£333,800

£412,200

LBR varying by cycle order*

£39,400

£114,200

£199,500

£287,200

£379,900

£474,400

U-IUI

      

LBR = 4.4%

£0

£30,700

£62,100

£94,100

£126,600

£159,700

LBR = 2%

£6,900

£45,300

£83,700

£122,300

£161,000

£199,900

LBR varying by cycle order±

£53,800

£141,100

£233,400

£326,800

£420,300

£514,000

C-IUI

      

LBR = 6.6%

£23,900

£76,300

£128,900

£181,600

£234,200

£286,800

LBR = 2.5%

£35,800

£102,100

£168,400

£234,700

£301,000

£367,300

 

No. of live births expected from full cycles of IVF that could be purchased by the estimated cost difference

S-IUI

      

LBR = 8.7%

3

9

15

20

27

33

LBR varying by cycle order*

3

9

16

23

30

38

U-IUI

      

LBR = 4.4%

0

2

5

7

10

13

LBR = 2%

1

4

7

10

13

16

LBR varying by cycle order±

4

11

19

26

33

41

C-IUI

      

LBR = 6.6%

2

6

10

14

19

23

LBR = 2.5%

3

8

13

19

24

29

  1. * LBR of S-IUI of 10%, 6%, 4%, 4%, 2%, 2% for cycles 1 to 6 respectively
  2. ± LBR of U-IUI of 5%, 3%, 2% 2%, 2%, 2% for cycles 1 to 6 respectively.
  3. Figures of cost differences are rounded to the nearest hundred.