ITEM# | QUESTION | †ANSWER |
---|---|---|
GKAI1 | The DNA sequences of two randomly selected healthy individuals of the same sex are 90-95% identical. | False (22%)** |
GKAI2 | Most common diseases, such as diabetes and heart disease, are caused by a single gene variant. | False (80%) |
GKAI3* | Common structural genetic variation (changes in the human genome such as deletions, duplications and large-scale copy-number variants) is important in health and disease. | True (90%) |
GKAI4 | All the genetic variation in an individual can be attributed to either spontaneous (i.e., de novo) or inherited changes in the human genome. | True (60%) |
GKAI5* | The variation in the human genome includes both disease-causing gene variants and variants that have no effect on health and disease. | True (92%) |
GKAI6 | Individual genetic variants are usually highly predictive of the manifestation of common disease. | False (60%) |
GKAI7 | Prevalence of many Mendelian diseases differs by racial groups. | True (69%) |
GKAI8 | Self-reported race is informative of a racial group’s genetic ancestral background. | True (39%) |