State | Proportion | Utility | Mean duration, L (years) | Cost, 2009 (€) | Comments | Example |
---|---|---|---|---|---|---|
Death | 0.078 | 0 | 3 | 3,831 | Duration here is expected mean survival without the event, as estimated as weighted average from Zegers et al. [29] | Vincristine administered by intrathecal route. |
Permanent disability | 0.047 | To be determined | 6 | 6,649 | Costs exclude long-term care. No data on mean duration, but a given adverse event is more likely to be fatal in an older person, so mean survival assumed to be a little longer than life years lost in those who died. | Haemorrhagic stroke in patient prescribed warfarin and macrolide antibiotics. |
Moderate disability | 0.617 | To be determined | 0.2 | 5,973 | Duration ≤6 months in 70% of cases (Baker et al. [30]) | Pulmonary embolism in large patient given standard (inadequate) dose of heparin. |
Minimal effect | 0.257 | To be determined | 0.05 | 2,979 | Transient urticarial rash in known allergic patient given penicillin. |