| The public, scenario A | (N = 533) |  | The public, scenario B | (N = 525) |  | P-value for difference |
---|---|---|---|---|---|---|---|
 | Coefficient (s.e.) | OR | MWTP | Coefficient (s.e.) | OR | MWTP |  |
Untreated responders & | Â | Â | Â | Â | Â | Â | Â |
   5% | 0.1748 (0.0266)** | 1.41 | 1,331 | 0.2577 (0.0270)** | 1.65 | 1,344 | 0.0241 |
   20% | 0.0367 (0.0265) | 1.23 | 796 | 0.0324 (0.0274) | 1.32 | 740 | 0.8487 |
   35% | −0.0429 (0.0276) | 1.13 | 487 | −0.0465 (0.0285) | 1.22 | 528 | 0.9315 |
   50% | −0.1686 (0.0466) | 1 | Ref | −0.2436 (0.0479)** | 1 | Ref |  |
Unnecessary treatment of non-responders †|  |  |  |  |  |  |  |
   5% | 0.1008 (0.0268)** | 1.24 | 827 | 0.2452 (0.0270)** | 1.50 | 1,080 | 0.0004 |
   20% | 0.0065 (0.0274) | 1.13 | 461 | 0.0377 (0.0288) | 1.22 | 524 | 0.6691 |
   35% | 0.0051 (0.0272) | 1.12 | 456 | −0.1251 (0.0281)** | 1.03 | 88 | 0.0115 |
   50% | −0.1124 (0.0470) | 1 | Ref | −0.1578 (0.0485)** | 1 | Ref |  |
Severity of side effects | Â | Â | Â | Â | Â | Â | Â |
   Mild | 0.3319 (0.0205)** | 2.10 | 2,882 | 0.3295 (0.0211)** | 2.24 | 2,165 | 0.3838 |
   Moderate | 0.0798 (0.0210)** | 1.63 | 1,905 | 0.1484 (0.0217)** | 1.87 | 1,679 | 0.0621 |
   Severe | −0.4117 (0.0293)** | 1 | Ref | −0.4779 (0.0303)** | 1 | Ref |  |
Likelihood of side effects | Â | Â | Â | Â | Â | Â | Â |
   5% | 0.2490 (0.0204)** | 1.62 | 1,861 | 0.2622 (0.0213)** | 1.75 | 1,497 | 0.2245 |
   50% | −0.0179 (0.0209) | 1.24 | 826 | 0.0340 (0.0214) | 1.39 | 885 | 0.2261 |
   95% | −0.2311 (0.0292)** | 1 | Ref | −0.2962 (0.0302)** | 1 | Ref |  |
Genetic test turnaround time | Â | Â | Â | Â | Â | Â | Â |
   2 days | 0.1213 (0.0210)** | 1.26 | 911 | 0.1266 (0.213)** | 1.27 | 650 | 0.4533 |
   7 days | −0.0076 (0.0208) | 1.11 | 411 | −0.0107 (0.0218) | 1.11 | 282 | 0.5396 |
   12 days | −0.1137 (0.0296)** | 1 | Ref | −0.1159 (0.0305)** | 1 | Ref |  |
Genetic test procedure | Â | Â | Â | Â | Â | Â | Â |
   Mouth swab | 0.2962 (0.0304)** | 1.75 | 2,162 | 0.3045 (0.0311)** | 1.73 | 1,474 | 0.9942 |
   Blood sample | 0.2863 (0.0320)** | 1.73 | 2,124 | 0.3882 (0.0332)** | 1.88 | 1,698 | 0.5738 |
   Tumor biopsy | −0.0416 (0.0326) | 1.25 | 853 | −0.0809 (0.0332)** | 1.18 | 440 | 0.8152 |
   Bone marrow biopsy | −0.2792 (0.0321)** | 0.98 | −68 | −0.3666 (0.0339)** | 0.89 | −325 | 0.6879 |
   Liver biopsy | −0.2617 (0.0636)** | 1 | Ref | −0.2452 (0.0675)** | 1 | Ref |  |
Neither (No test) | −0.6323 (0.0379)** | 0.53 | −2,451 | −0.4967 (0.0389)** | 0.61 | −1,332 | 0.0169 |
Genetic test cost | −0.00026 (0.00003)** |  | Ref | −0.00037 (0.00003)** |  | Ref | 0.0091 |
   McFadden’s LRI | 0.17 |  |  |  |  |  |  |
   Adjusted Estrella | 0.33 |  |  |  |  |  |  |
   Log-likelihood Ratio | 6216.5 |  |  |  |  |  |  |
   AIC | 31050 |  |  |  |  |  |  |
   Schwartz Criterion | 31329 |  |  |  |  |  |  |