Variable | Mean (SE) | Sources |
---|---|---|
Clinical Variable (Transitional Probability) | ||
RI-HSCT | ||
Q1 state --> Death | Vary | Cohort, MOPH [10] |
Q1 state --> BT-ICT | 0.00003 | Cohort |
Q2 state --> Death | Vary | Cohort, MOPH [10] |
Q2 state --> BT-ICT | 0.0003 | Cohort |
Q3 state --> Death | Age-specific Mortality | MOPH [10] |
Q3 state --> BT-ICT | 0.00 | Assumption |
Q4 state --> Death | Age-specific Mortality | MOPH [10] |
Q4 state --> BT-ICT | 0.00 | Assumption |
Iron chelation state --> Death | Age-specific Mortality | MOPH [10] |
Iron chelation state--> BT-ICT | 0.00 | Assumption |
Post RI-HSCT --> Death | Age-specific Mortality | MOPH [10] |
Post RI-HSCT--> BT-ICT | 0.00 | Assumption |
BT-ICT (Severe Thalassemia patients) | ||
BT-ICT Thal --> BT-ICT Thal with cardiac | 0.0114 | Borgna-Pignatti C et al.[11] |
BT-ICT Thal --> Death | Vary | |
BT-ICT Thal with cardiac --> Death | Vary | |
Cost Variable (convert to US $) *,! | ||
RI-HSCT | Â | Â |
Pre-BMT | Â | Â |
Direct Medical Cost | 1,330 (438) | Hospital Database# |
Direct Non Medical Cost | 75 (21) | Survey |
Indirect Cost | 175 (42) | Survey |
Q1 state | Â | Â |
Direct Medical Cost | 1,226 (169) | Hospital Database# |
Direct Non Medical Cost | 458 (51) | Survey |
Indirect Cost | 945 (105) | Survey |
Q2 state | Â | Â |
Direct Medical Cost | 1,710 (381) | Hospital Database# |
Direct Non Medical Cost | 335 (41) | Survey |
Indirect Cost | 691 (85) | Survey |
Q3 state | Â | Â |
Direct Medical Cost | 1,628 (538) | Hospital Database# |
Direct Non Medical Cost | 259 (30) | Survey |
Indirect Cost | 535 (62) | Survey |
Q4 state | Â | Â |
Direct Medical Cost | 878 (282) | Hospital Database# |
Direct Non Medical Cost | 253 (32) | Survey |
Indirect Cost | 522 (66) | Survey |
Iron chelation state | Â | Â |
Direct Medical Cost | 1,120 (238) | Hospital Database# |
Direct Non Medical Cost | 539 (112) | Survey |
Indirect Cost | 1,111 (230) | Survey |
Post RI-HSCT state | Â | Â |
Direct Non Medical Cost | 1,548 (411) | Hospital Database# |
Direct non Medical Cost | 299 (146 | Survey |
Indirect Cost | 617 (301) | Survey |
BT-ICT (Severe Thalassemia patients) | ||
Severe thalassemia patients without cardiac complications | Â | Â |
Direct Medical Cost | 1,187 (137) | Riewpariboon et al. [28] |
Direct Non Medical Cost | 1,240 (232) | Leelahavaring et al. [29] |
Indirect Cost | 636 (221) | Leelahavaring et al. [29] |
Severe thalassemia patients with cardiac complications | Â | Â |
Direct Medical Cost | 1,187 (137) | Riewpariboon et al. [28] |
Direct Non Medical Cost | 1,240 (232) | Leelahavaring et al. [29] |
Indirect Cost | 636 (221) | Leelahavaring et al. [29] |
Effectiveness Variable | Â | Â |
RI-HSCT | Â | Â |
Q1 state | 0.59 (0.30) | Survey |
Q2 state | 0.59 (0.30) | Survey |
Q3 state | 0.59 (0.30) | Survey |
Q4 state | 0.59 (0.30) | Survey |
Iron chelation state | 0.88 (0.06) | Survey |
Post-RI-HSCT | 0.90 (0.05) | Survey |
BT-ICT (Severe Thalassemia patients) | Â | Â |
Severe thalassemia patients without cardiac complications | 0.61 (0.03) | Osborne et al. [33] |
Severe thalassemia patients with cardiac complications | 0.46 (0.02) | Osborne et al. [33] |