Author (year) | Setting | Design | Intervention | Reduction of CA-BSI | Level of evidence |
---|---|---|---|---|---|
Wirtschafter et al. (2010) | NICU | A | Proper CVC insertion, hand hygiene promotion, closed tubing system, improved hub care | From 4.32 to 3.22 per 1000 line-days | 2- |
Sannoh et al. (2010) | NICU | B | Hand hygiene promotion, proper hub care using chloorhexedine with alcohol, glove use promotion, CVC documentation | From 23 to 12 per 1000 line-days* | 2++ |
Bizzarro et al. (2010) | NICU | B | Proper CVC placement, promotion of hand hygiene, daily evaluation CVC need, infection surveillance, dressing replaced on indication | From 8.40 to 1.28 cases per 1000 line-days* | 2+ |
Andersen et al. (2005) | NICU# | B | Hand hygiene promotion, maximum barrier during CVC insertion, daily evaluation need for CVC removal | From 21% to 9% (P=0.05, confidence intervals 0.19–1.0)* | 2+ |
Costello et al. (2008) | PICU | C | Hand hygiene promotion, daily evaluation need for CVC removal, CVC insertion kid | From 7.8 to 4.7 and to 2.3 per 1000 line-days | 2- |
McKee et al. (2008) | PICU | D | Proper insertion and nursing care, empower nurses to stop the insertion procedure if guidelines were not followed, using a checklist to ensure adherence to the guidelines, providing weekly performance feedback, promotion of hand hygiene, chlorhexedine skin preparation, | From 5.2 to 3.0 per 1000 line-days* | 2+ |
Jeffries et al. (2009) | PICU | E | Maximum sterile barrier during CVC insertion, hand hygiene promotion, apply transparent dressing, prepare skin with anti and/ or detergent chlorhexidine gluconate 2%, | From 6.3 to 4.3 per 1000 line-days* | 2+ |
Miller et al. (2010) | PICU | F | Disinfect catheter site using chlorhexedine, maximum barrier, full barrier during pre-packages of the insertion tray, daily assess CVC need, gauze change every 2 days | From 5.4 to 3.1 per 1000 line-days* | 2+ |
Wheeler et al. (2011) | Children’s hospital-wide | D | Full barrier precautions, chlorhexedine skin preparation with 2 minutes scrub and 1 minute air dry, use of insertion checklist, staff empowerment to stop the insertion procedure, daily assess CVC need, promotion of hand hygiene, chlorhexidine-impregnated sponge placed at insertion site, glove use for all CVC manipulations, change dressing every 7 day or on indication earlier, replace tubing sets no more than 72 hour, cap change every 7 day | From 3 to <1 per 1000 line-days* | 2+ |
Chuengchitraks et al. (2010) | PICU | G | Promotion of hand hygiene, maximal barrier precautions, provide skin antiseptic, optimal catheter site selection | From 2.6 to 2.4 per 1000 line-days | 2- |