Table 2 Patient characteristics
With fixed-dose combination drugs (cases) | Without fixed-dose combination drugs (controls) | p (χ2 tests) | |||
|---|---|---|---|---|---|
Number of patients | 542 | 9664 | |||
Gender | 0.1735 | ||||
Male | 198 | 36.5% | 3814 | 39.5% | |
Age category | 0.2087 | ||||
≤64 years | 212 | 39.1% | 3729 | 38.6% | |
65–74 years | 153 | 28.2% | 3047 | 31.5% | |
≥75 | 177 | 32.7% | 2888 | 29.9% | |
Drug use before index | <.0001 | ||||
ARB and CCB combination | 405 | 74.7% | 5269 | 54.5% | |
ARB alone | 104 | 19.2% | 3938 | 40.7% | |
Number of concomitant drugs | 0.4567 | ||||
7 or more | 74 | 13.7% | 1214 | 12.6% | |
Diabetes drugs | 0.0582 | ||||
Users | 153 | 28.2% | 2379 | 24.6% | |
Hyperlipidemia drugs | 0.8094 | ||||
Users | 236 | 43.5% | 4157 | 43.0% | |
Prescribers’ characteristics | |||||
Doctors at clinics (no bed) | 111 | 20.5% | 993 | 10.3% | <.0001 |
Cardiovascular specialists | 172 | 31.7% | 2457 | 25.4% | 0.0011 |