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Table 1 Characteristics of patients (N = 600) according to HCV treatment initiation during follow-up (ANRS CO13 HEPAVIH cohort.)

From: Engaging HIV-HCV co-infected patients in HCV treatment: the roles played by the prescribing physician and patients' beliefs (ANRS CO13 HEPAVIH cohort, France)

 

HCV treatment initiation

  
 

NO

% or median

[IQR]

N = 476

Yes

% or median

[IQR]

N = 124

Total

sample

% or median

[IQR]

N = 600

p-value§

Female gender

34

27

33

0.12

Age

44 [41-48]

43 [41-47]

44 [41-47]

0.06

Born outside France

19

20

19

0.79

HIV transmission group

   

0.51

   IV drug use

63

64

63

 

   Heterosexual

16

12

15

 

   Homosexual

10

14

11

 

   Other or unknown

11

10

10

 

HCV genotype

   

0.48

   1 or 4

66

72

67

 

   2 or 3

18

25

20

 

   5

1

0

1

 

   Unknown

15

2

13

 

ASAT

47 [34-71]

52 [37-94]

48 [35-74]

0.06

ALAT

52 [35-84]

65 [42-91]

56 [35-87]

0.04

Previous exposure to IFN (not PEG) + ribavirine

9

9

9

0.95

Severe fibrosis (Metavir F3 or F4)

22

45

27

< 10-3

Fibrosis score

    

   F0-F1

59

40

55

< 10-3

   F2

18

16

18

 

   F3

7

17

9

 

   F4

15

28

18

 

CD4 < 200/mm3

12

11

12

0.75

Undetectable HIV viral load

62

60

81

0.69

Antidepressants use

20

19

20

0.93

Harmful alcohol consumptiona

11

15

12

0.25

Daily cannabis use

15

18

16

0.52

Cocaine use

8

10

9

0.59

Heroin use

2

4

3

0.47

More than 20 cigarettes consumed per day

32

33

32

0.88

Depressive symptomsb

40

41

40

0.80

Number of self-reported symptoms

7 [2-14]

6 [2-14]

7 [2-14]

0.53

Receiving ART

89

92

89

0.32

Number of years since first HIV positive test

17 [13-20]

16 [13-20]

17 [13-20]

0.11

Number of years since first HCV positive test

11 [7-15]

9 [4-13]

10 [6-15]

0.004

Patients negative beliefs HCV treatmentsc

42

29

39

0.03

Patient- high adherence as perceived by the physician

38

47

40

0.10

Patient- alcohol problems as perceived by the physician

20

21

20

0.72

Patient- suicide attempts as reported by the physician

8

8

8

0.99

Patient- history of multiple treatments for depression as reported by the physician

19

20

19

0.77

Followed up by a general practitioner

22

39

26

0.001

Liver biopsy at enrolment

32

52

36

< 10-3

  1. a Defined as the consumption of more than 90 alcohol units/month for men and 60 alcohol units/month for women
  2. b Patients were defined as having depressive symptoms if CES-D > 17 for men and > 23 for women
  3. c Beliefs were measured on a 1-4 visual analogue scale. Believes HCV treatment to be non-effective (score 1) and associated with large number of side effects (score 4)
  4. § A Chi-squared and T-test was performed for qualitative and quantitative variables respectively
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BMC Health Services Research

ISSN: 1472-6963

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