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Table 3 Alcohol dependence, illicit drug dependence and tobacco use diagnoses: comparison of administrative diagnoses against chart notation during the past 12 months prior to and including the index date

From: Validation of key behaviourally based mental health diagnoses in administrative data: suicide attempt, alcohol abuse, illicit drug abuse and tobacco use

 

Alcohol Problems, Abuse/Dependence

 

Unweighted Estimates, % b (N in fraction)

Sample

Agreement

Sensitivity

Specificity

PPV

NPV

Suicide Death

90 (331/368)

74 (90/121)

98 (241/247)

94 (90/96)

89 (241/272)

Control

90 (327/362)

54 (28/52)

96 (299/310)

72 (28/39)

93 (299/323)

AD New User

90 (515/571)

63 (73/116)

97 (442/455)

85 (73/86)

91 (442/485)

Combineda

90 (658/730)

68 (118/173)

97 (540/557)

87 (118/135)

91 (540/595)

 

Weighted Estimates, % b (95% confidence interval)

Suicide Death

90 (87, 94)

78 (70, 87)

97 (95, 100)

94 (88, 100)

89 (84, 93)

Control

90 (85, 95)

55 (34, 75)

97 (95, 99)

80 (67, 94)

91 (86, 96)

AD New User

91 (87, 94)

59 (46, 73)

98 (96, 100)

86 (75, 97)

91 (88, 95)

Combineda

90 (85, 95)

55 (35, 75)

97 (95, 99)

80 (68, 93)

91 (86, 96)

 

Illicit Drug Use/Abuse/Dependence

 

Unweighted Estimates, % b (N in fraction)

 

Agreement

Sensitivity

Specificity

PPV

NPV

Suicide Death

90 (331/368)

74 (26/35)

92 (305/333)

48 (26/54)

97 (305/314)

Control

96 (348/362)

58 (11/19)

98 (337/343)

65 (11/17)

98 (337/345)

AD New User

93 (533/571)

70 (38/54)

96 (495/517)

63 (38/60)

97 (495/511)

Combineda

93 (679/730)

69 (37/54)

95 (642/676)

52 (37/71)

97 (642/659)

 

Weighted Estimates, % b (95% confidence interval)

Suicide Death

90 (86, 94)

78 (62, 94)

92 (88, 95)

51 (35, 67)

97 (95 99)

Control

97 (94, 99)

61 (30, 91)

99 (97, 100)

70 (43, 96)

98 (96, 100)

AD New User

91 (85, 96)

54 (24, 85)

95 (92, 98)

58 (37, 79)

94 (89, 100)

Combineda

97 (94, 99)

61 (33, 89)

99 (97, 100)

69 (45, 93)

98 (96, 100)

 

Tobacco Use

 

Unweighted Estimates, % b (N in fraction)

 

Agreement

Sensitivity

Specificity

PPV

NPV

Suicide Death

73 (267/368)

42 (70/167)

98 (197/201)

95 (70/74)

67 (197/294)

Control

76 (274/362)

36 (46/128)

97 (228/234)

89 (46/52)

74 (228/310)

AD New User

74 (424/571)

40 (95/237)

99 (329/334)

95 (95/100)

70 (329/471)

Combineda

74 (541/730)

39 (116/295)

98 (425/435)

92 (116/126)

70 (425/604)

 

Weighted Estimates, % b (95% confidence interval)

Suicide Death

70 (64, 76)

42 (33, 52)

97 (94, 100)

94 (87, 100)

63 (56, 70)

Control

76 (70, 82)

39 (27, 50)

98 (96, 100)

91 (83, 99)

73 (66, 80)

AD New User

77 (72, 82)

44 (34, 54)

99 (97, 100)

95 (90, 100)

73 (67, 79)

Combineda

76 (70, 82)

39 (27, 50)

98 (96, 100)

91 (84, 99)

73 (66, 80)

  1. Note: For alcohol dependence, kappa values are 0.76 for suicide cases, 0.57 for controls and 0.66 for AD new users. For illicit drug dependence, kappa values are 0.53 for suicide cases, 0.55 for controls and 0.63 for AD new users.
  2. Abbreviation: NA is not available, AD is antidepressant; PPV is positive predictive value of an administrative diagnosis; NPV is the negative predictive value of an administrative diagnosis.
  3. a Combined sample of suicide deaths and controls
  4. b Rounded to a whole number