Therapeutic Plasma Exchange (TPE) | Intravenous immunoglobulin infusion (IVIg) |
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• Five plasma exchanges totaling 250 ml/kg total plasma volume replacement • 80% volume replacement with 5% human albumin; 20% volume with saline or other crystalloid • 70 kg mean body weight • Non-tunneled subclavian or intrajugular catheter placed in all patients | • 5 IVIg infusions totaling 2.0 g/kg • 70 kg mean body weight • Infusions started and monitored by a nurse |