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Table 3 Basic assumptions applied regarding therapeutic plasma exchange and intravenous immunoglobulin infusion treatment regimens in study

From: Cost-minimization analysis of the direct costs of TPE and IVIg in the treatment of Guillain-Barré syndrome

Therapeutic Plasma Exchange (TPE)

Intravenous immunoglobulin infusion (IVIg)

• Five plasma exchanges totaling 250 ml/kg total plasma volume replacement

• 80% volume replacement with 5% human albumin; 20% volume with saline or other crystalloid

• 70 kg mean body weight

• Non-tunneled subclavian or intrajugular catheter placed in all patients

• 5 IVIg infusions totaling 2.0 g/kg

• 70 kg mean body weight

• Infusions started and monitored by a nurse