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Table 3 Alert Interventions to decrease benzodiazepine use

From: Improving the use of benzodiazepines-Is it possible? A non-systematic review of interventions tried in the last 20 years

Study

Location

Intervention Design:

Alert Interventions targeted at GPs

Study Design and Size

Result

Follow up

Simon et al, 2006 [72]

USA - Oregon & Washington

1 = age Specific (> 65 years) alert for long acting BZs. 2 = alerts + academic detailing (group education + follow-up letter).

Cluster randomized trial

239 clinicians

No sig decrease in prescribing to elderly. No difference between alerts (decrease of 3.0 dispensed medications per 10,000 members) and alerts + academic detailing (decrease of 19.7 dispensed medications per 10,000)

18 months post intervention

Monane et al, 1998

[73]

America

1 = age specific (> 65 years) alert system at pharmacy (mail order and retail). If medication is deemed to be inappropriate then conversation between pharmacist and prescriber occurred. 2 = control.

Population based cohort

2.3 million people >65 years filled a script during study period

Sig difference between intervention (40% of cases) and control (2%) for the change of prescriptions for long acting BZs. Sig difference between control (2%) and intervention (25%) for change to prescriptions of short acting BZs that exceeded the maximum daily dose.

1 year study (measured total number of changes over 1 year)

  1. BZ = benzodiazepine, Sig = statistically significant (p < 0.05), GP = General Practitioner