Table 4 Drug group and diagnoses most frequently associated with ADR.
From: Trends of adverse drug reactions related-hospitalizations in Spain (2001-2006)
ICD-9-CM code | Frequency | Percentage CI 95% | |
|---|---|---|---|
Drug group | |||
Antineoplastic and immunosuppressive drugs | E933.1 | 75,760 | 21.5 (21.2-21.7) |
Adrenal cortical steroids | E932.0 | 47,539 | 13.5 (13.1-13.8) |
Anticoagulants | E934.2 | 26,546 | 7.5 (7.1-7.8) |
Cardiotonic glycosides | E942.1 | 24,662 | 7.0 (6.6-7.3) |
Antibiotics | E930.8-E930.9 | 22,144 | 6.3 (5.9-6.6) |
Diuretics | E944.4 | 21,818 | 6.2 (5.8-6.5) |
Antirheumatics | E935.6 | 12,859 | 3.6 (3.2-.39) |
Cardiac rhythm regulators | E942.0 | 11,943 | 3.4 (3.0-3.7) |
Unspecified drug or medicinal substance | E947.9 | 11,134 | 3.2 (2.8-3.5) |
Diagnoses | |||
Neutropenia, unspecified | 288.0 | 17,803 | 5.0 (4.6-5.3) |
Obstructive chronic bronchitis | 491.21 | 17,239 | 4.9 (4.5-5.2) |
Congestive heart failure | 428.0 | 11,135 | 3.1 (2.7-3.4) |
Encounter for chemotherapy and immunotherapy for neoplastic conditions | V58.1 | 10,840 | 3.0 (2.6-3.3) |
Pneumonia | 486 | 10,244 | 2.9 (2.5-3.2) |
Diseases of respiratory system | 519.8 | 6,951 | 1.9 (1.5-2.2) |
Aplastic anemias | 284.8 | 5,985 | 1.7 (1.3-2.0) |
Other and unspecified adverse effect of drug | 995.2 | 4,968 | 1.4 (1.0-1.7) |
Acute renal failure | 584.9 | 4,787 | 1.3 (0.9-1.6) |
Toxic gastroenteritis and colitis | 558.2 | 4,444 | 1.2 (0.8-1.5) |